DEREK AND ADDISON�S DISAGREEMENTS BECOME PROFESSIONAL WHEN
THEIR CLOSE FRIENDS HAVE A MEDICAL CRISIS, ON ABC�S �GREY�S ANATOMY�
�Let It Be� � Derek and Addison Shepherd�s professional relationship is challenged when their closest friends come to Seattle Grace seeking a radical, preemptive operation to avoid breast and ovarian cancer. Meanwhile, George can�t understand why a patient who fell five stories doesn�t seem happy to have survived; an elderly gentleman makes a difficult decision upon learning that his wife has only a few months to live; Cristina and Burke try to have a �normal� date, and Chief Webber is disappointed by Bailey�s fellowship decision -- until he learns her reasons -- on �Grey�s Anatomy,� SUNDAY, NOVEMBER 13 (10:01-11:00 p.m., ET) on the ABC Television Network.
�Grey�s Anatomy� stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Isaiah Washington as Preston Burke, Katherine Heigl as Isobel �Izzie� Stevens, Justin Chambers as Alex Karev, T.R. Knight as George O�Malley, Chandra Wilson as Miranda Bailey and James Pickens, Jr. as Richard Webber.
Guest starring are Kate Walsh as Addison Shepherd, Shelley Berman as Jed, Joseph Lyle Taylor as Weiss, Arija Bareikis as Savannah, Brittany Ishibashi as Talia, Geoffrey Rivas as Stu and Janet Rotblatt as Esme.
�Let It Be� was written by Mimi Schmir and directed by Lesli Glatter.
�Grey�s Anatomy� is broadcast in 720 Progressive (720P), ABC�s selected HDTV format, with 5.1-channel surround sound and Spanish subtitles via secondary closed captioning.
A TV parental guideline will be assigned closer to airdate.