(NOTE TO EDITORS: The following episode of CRIMINAL MINDS has been substituted for the one previously scheduled for April 19).

A QUICK CHANGE ARTIST ON A KILLING SPREE TAKES GIDEON, HOTCHNER AND THEIR TEAM ON A WILD CHASE THROUGHOUT THE SOUTH, ON "CRIMINAL MINDS," WEDNESDAY, APRIL 19

"Charm and Harm" -- Gideon, Hotchner and their team race to catch a serial killer on the run across the South, on CRIMINAL MINDS, Wednesday, April 19 (9:00-10:00 PM, ET/PT) on the CBS Television Network. Felix Alcala directed the episode from a script written by Debra J. Fisher and Erica Messer.

The serial killer changes his appearance like a chameleon in order to elude authorities and continue his killing spree. It is up to the Behavioral Analysis Unit to look beyond his multiple appearances and profile the man underneath in order to locate him before he takes his next victim.

Jason Gideon: Mandy Patinkin
Aaron Hotchner: Thomas Gibson
Elle Greenaway: Lola Glaudini
Derek Morgan: Shemar Moore
Dr. Spencer Reid: Matthew Gray Gubler
Jennifer: A.J. Cook
Garcia: Kirsten Vangsness
Mark Gregory: Andy Comeau
Spec. Agt. Raymond McCarthy: Mark Totty
Room Service: Dajuan Johnson
Hank Bloomberg: Michael W. Catlin
Doug Gregory: Robert Pine
Jenna Alban: Trary Maddalone
Agent #1: Eltony Williams
Motel Manager: Sathya Jesudesson
Allyson Glennon: Alicia Ziegler
Motel Clerk: Brian Groh
Kelly Dalton: Joey Honsa

RATING: To Be Announced