MEREDITH AND CRISTINA'S FRICTION STARTS TO AFFECT THEIR WORK, ON ABC'S "GREY'S ANATOMY"

Jason George ("Mistresses") Guest Stars

"Two Against One" - The issues between Meredith and Cristina hit a boiling point when one of them ultimately betrays the other at the hospital. Derek tells Jackson that he needs to let go and allow the second year doctors to work on his patients, and April and Matthew make a bold decision about their relationship. Meanwhile, Bailey has difficulties with Ben's return, on "Grey's Anatomy," THURSDAY, NOVEMBER 7 (9:00-10:00 p.m., ET) on the ABC Television Network.

"Grey's Anatomy" stars Ellen Pompeo as Meredith Grey, Patrick Dempsey as Derek Shepherd, Sandra Oh as Cristina Yang, Justin Chambers as Alex Karev, Chandra Wilson as Miranda Bailey, James Pickens, Jr. as Richard Webber, Sara Ramirez as Callie Torres, Kevin McKidd as Owen Hunt, Jessica Capshaw as Arizona Robbins, Jesse Williams as Jackson Avery, Sarah Drew as April Kepner, Camilla Luddington as Jo Wilson, Gaius Charles as Shane Ross, Jerrika Hinton as Stephanie Edwards and Tessa Ferrer as Leah Murphy.

Guest cast TBA.

"Two Against One" was written by Meg Marinis and directed by Kevin McKidd.

"Grey's Anatomy" is broadcasted in 720 Progressive (720P), ABC's selected HTV format, with 5.1-channel surround sound. A TV parental guideline will be assigned closer to airdate.

For more information on "Grey's Anatomy" please visit ABC.com.