SERIES SYNOPSIS:

Mayor Tom Kane (Kelsey Grammer) sits like a spider at the center of Chicago's web of power; a web built on a covenant with the people. They want to be led, they want disputes settled, jobs dispensed, and loyalties rewarded. If he achieves all this through deception and immorality, so be it. As long as he gets the job done, they look the other way.

Yet despite being the most effective mayor in recent history, a degenerative brain disorder is ripping everything away from him. He can't trust his memory, his closest allies, or even himself.

Kane's wife Meredith (Connie Nielsen) knows nothing. Theirs is a marriage of convenience. Kitty O'Neil (Kathleen Robertson), Kane's political aide, has her suspicions but stays silent. Kane's chief of staff, Ezra Stone (Martin Donovan), has no illusions about the stakes involved and doesn't ask questions. And State Treasurer Ben Zajac (Jeff Hephner) is too concerned with his own political ambitions to notice anything unusual.

Only Emma (Hannah Ware), Kane's estranged daughter, has a chance of learning his secret. This is going to be the toughest term yet for the Boss.