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IT'S "GLEE" AGAINST THE MUSIC WHEN BRITNEY SPEARS GUEST-STARS ON THE HIT SERIES TUESDAY, SEPTEMBER 28, ON FOX

New Directions performs Britney Spears' most iconic and memorable songs, including "Toxic," "...Baby One More Time" and "Me Against The Music," and the pop princess herself makes a special cameo appearance on an all-new, sure-to-be-fan-favorite episode of GLEE airing Tuesday, Sept. 28 (8:00-9:00 PM ET/PT) on FOX.

"Working on GLEE was an amazing experience," said Spears. "The cast is so talented, and I really had an incredible time working with Ryan Murphy."

In the "Britney/Brittany" episode, MR. SCHUESTER (Matthew Morrison) insists that the glee club perform adult contemporary music at the school assembly, but the kids have other plans. As New Directions mounts its campaign to perform Britney Spears' greatest hits, they learn that their own BRITTANY (Heather Morris) has a connection to the famous performer. Meanwhile, Will meets EMMA's (Jayma Mays) new love interest, DR. CARL (John Stamos), who sparks a rivalry between the two men as they vie for her attention.

The sophomore season of GLEE, the biting musical comedy that has quickly become a pop-culture phenomenon, kicks off tomorrow, Tuesday, Sept. 21 (8:00-9:00 PM ET/PT), with the "Audition" season premiere episode. After a tough loss at Regionals, the glee club is back as the underdogs of McKinley High. When the school is faced with even more budget cuts, Mr. Schuester pushes the kids to help recruit new members for the club. RACHEL (Lea Michele) and FINN (Cory Monteith) disagree on new recruits, including SAM EVANS (newcomer Chord Overstreet) and SUNSHINE CORAZON (international pop star Charice), and aren't sure they will be able to come together in perfect harmony. Meanwhile, Sue meets her match when she goes head-to-head with COACH BEISTE (Dot Marie Jones), the new head of the football team.

GLEE is produced by Ryan Murphy Television in association with 20th Century Fox Television. Ryan Murphy, Brad Falchuk and Ian Brennan are co-creators of the series. Murphy, Falchuk, Brennan and Dante Di Loreto serve as executive producers. Become a fan of GLEE on Facebook at facebook.com/glee and follow the series on Twitter at twitter.com/gleeonfox.